Dr. Vittorio Gentile is currently working as Aggregate professor of Biochemistry at the Department of Biochemistry, Biophysics and General Pathology, II University of Naples, Italy. He completed his Ph.D. in Biochemical Sciences, 1st Medical School, University of Naples and Bari, Italy. He has one patent and numerous publications. He received many awards and honors during his career.
Dr. Vittorio Gentile is serving as the eminent member of several professional societies, and he is an Editorial board member and reviewer of many peer reviewed Journals. He is a recognized expert in the transglutaminase research area and has a strong background in the molecular biology and biochemical aspects of the transglutaminase (TG) enzymes expression, activity and function. His work has been focused on the tTG (TG2) characterization in normal and pathological cellular events (cell growth and differentiation, adhesion, apoptosis) by molecular biology, immunological and biochemical studies.
Dr. Vittorio Gentile’s research interest focuses on Cloning and characterisation of the gene for human tissue transglutaminase. Transfection of the human tissue transglutaminase cDNA in Balb-C 3T3 mouse fibroblasts: molecular and cellular characterisation of the stable transfected cell lines. Site direct mutagenesis of the human tissue transglutaminasecDNA. Characterisation of rat intestinal transglutaminase and studies on transglutaminase-mediated modifications of gliadins in relation to the Coeliac Disease. Characterization of the human tissue transglutaminase as a mediator of the cell signal transduction pathway. Studies on the possible involvement of transglutaminases in the pathogenesis of neurodegenerative diseases.
