All Recent Articles

Evaluation of Heart Block in Inferior Wall Myocardial Infarction in context of Intervention: Temporary Pacemaker Implantation Versus Conservative Medical Management, a Single Centre Experience from Eastern India
Association between Inferior wall Myocardial infarction (IWMI) and various degree of heart block is well known. However, most of these blocks are transient. Objective of this study was to re-evaluate ...
Transient Drug-Induced Myopia
Myopia (nearsightedness) is a refractive error, a condition in which the cornea and lens of the nonaccommoding eye have too much plus power for the length of eye. As a result, images of distant object...
Structural and Optical Characteristics of Cu Doped Sno2 Nanostructures
Copper doped tin oxide nanostructures were prepared by sol-gel method. Before that tin oxide and copper nanoparticles were synthesized using sol-gel and their structural and Optical properties were st...
Elastomeric Clay Nanocomposites Prepared by Colloidal Route: Study of Interrelationship of Structure and Physical-Chemistry Properties
Nanocomposites of SBR and NBR with Laponite were synthesized by the colloidal route and were homogeneous at the nanometer scale. ...
Acetabular Reconstruction Using Massive Allografts for Combined Cavitary and Segmental Defects
Acetabular reconstruction in cavitary, segmental defects and pelvic discontinuity is a technically challenging surgical procedure. Today in orthopaedic surgery there are some available solutions to fa...
Efficacy of Subcutaneous Tocilizumab for the Treatment of Refractory Large Vessel Vasculitis in a Patient with Latent Tuberculosis Infection
Tocilizumab (TCZ), a specific IL-6 inhibitor, has been shown to be effective and well tolerated in the treatment of refractory large-vessel vasculitis with monthly intravenous (i.v) infusions of 8 mg/...
Evaluation of Heart Block in Inferior Wall Myocardial Infarction in context of Intervention: Temporary Pacemaker Implantation Versus Conservative Medical Management, a Single Centre Experience from Eastern India
Association between Inferior wall Myocardial infarction (IWMI) and various degree of heart block is well known. However most of these blocks are transient. Objective of this study was to re-evaluate w...
Early Peripheral Blood Blast Clearance: A New Chemosensitivity Indicator for Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a highly heterogeneous disease, and cytogenetics and molecular markers play important roles in the diagnosis, treatment, and prognosis of AML. Although cytogenetic kary...
Knee Infection Caused By Candida Albicans Following A Knee Arthroscopy - A Case Report
Candidiasis is a disease caused by the infection of a fungus, Candida albicans, which is more commonly observed at the skin, oral and genital mucosa, and less frequently (and secondary to its dissemin...
The Antioxidant Flavonoids, Orientin and Vicenin Enhance Repair of Radiation-Induced Damage
Orientin (Ot) and vicenin (Vc), two water soluble flavonoids isolated from the Indian Holy Basil, are potent radioprotectants, but the mechanisms of protection are not fully understood. In the present...
Cancer Stem Cells in Tumors Arisen from Digestive Organs
The digestive system encompasses several organs in which tumors occur with an elevated prevalence and mortality worldwide. Increasing evidence shows that cancer stem cells (CSCs) may play a critical r...
Basal Cell Adenoma of the Parotid Gland: Case Report
Basal cell adenomas are rare form of monomorfic adenomas of the parotid gland. This rare form of the tumors are mostly seen on suprafacial part of the parotid gland. Basal cell adenomas are well demar...
The Sea Star Igkappa Gene: Effects Against Human Cancerous Cells
It was shown 32 years ago that the sea star axial organ cells (AO cells) produced a spontaneous cytotoxicity against mouse cancerous cells. Recently, we discovered a sea star Igkappa gene with immune ...
A Double Phase Culture System: An Economic and Time Saving Protocol for In Vitro Propagation of Plant
Low cost and time saving tissue culture techniques by improving process efficiency and better utilization of resources without compromising the quality of the plants are of high priority for commercia...
Administration of Vasoconstrictor, But Not Volume Expander Prevents Maternal Hypotension During Spinal-Epidural Anesthesia For Elective Cesarean Section
To determine the best management option for preventing maternal hypotension after combined spinal-epidural anesthesia (CSEA) in elective cesarean section patients. A total of 240 full-term, single pre...
Human Osteoblast Growth and Maturation in Response to Metformin and the Thienopyridone, A769662
Metformin (Met) is a biguanide drug widely used in the treatment and management of non insulin-dependent diabetes mellitus. In recent years it has emerged that Met, by stimulating adenosine monophosph...
Super-Innervation of a Free Latissimus Dorsi Flap in Facial Reanimation: A Novel Strategy for Supplementing Muscle Innervation
The gold-standard for facial reanimation in facial palsy involves a first stage crossed facial nerve graft and a second stage free muscle flap transfer, with a single neurorrhaphy of the muscle flap n...
Preparation and Characterization of Biodegradable Glimepiride Loaded PLA Nanoparticles by o/w Solvent Evaporation Method Using High Pressure Homogenizer: A Factorial Design Approach
Glimepiride is used for the treatment of type 2 diabetes mellitus, one of the third generation sulfonylurea drugs having poor aqueous solubility, slow dissolution rate and low elimination half life. T...
Role of memory formation (with emphasis on Hippocampal memory formation) and retrieval in cognitive learning
We are virtually learning all the time from our sensory stimuli. Sometimes we do it consciously and sometimes unconsciously. Basically, we absorb certain information from outside, convert them to suit...
A Rare Case of Vanishing Lung Syndrome
Vanishing lung syndrome (VLS) or idiopathic giant bullous emphysema is a rare condition characterized by giant bulla in one or both upper lobes of the lung, occupying at least one third of hemithorax....
Immunological Genetic Variants Underlying Endometriosis
Endometriosis is a common chronic gynaecologic disease defined as presence of endometrial tissue outside the uterine cavity, primarily on pelvic peritoneum and ovary, which affects 3-20% of women in t...
A Case Report of a Paediatric Intestinal Evisceration by Road Traffic Accident in Nepal
Road traffic accidents are on a rise with the number of vehicles increasing on the roads every day. With it the morbidity and the mortality associated with such accidents including both the people ins...
Concepts of Process Validation in Solid Dosage Form [Tablet] An Overview
Drugs having an important role in curing the various diseases in health care. Therefore, drugs must be manufactured to achieve a predictable therapeutic response with highest quality levels. End produ...
Ageing Associated Changes in Macromolecule Synthesis in the Endocrine Organs as Revealed by Microscopic Radioautography
The endocrine system of men and experimental animals consists of several endocrine organs. The term “Cell Ageing” initially means how the cells change due to their ageing. It contains 2 meanings, ...
Cold-Shock Stress Induces Formation of a Biopolymer Flocculant by Bacillus alvei NRC-14 under Static Incubation Conditions
Bacillus alvei NRC-14, a soil bacterial isolate, was found to exhibit multiple-adaptive response when exposed to abiotic stress factors. In the present study, chemical and flocculation properties of a...
Autologous Bone Marrow Therapy to Operative Site Following Modified Radical Mastectomy to Prevent Flap Complications
Breast cancer is the second leading cause of cancer-related deaths, second to lung cancer, with approximately 40,000 deaths caused by breast cancer annually. Breast cancer is also a global health prob...
Mushroom Spores in the Stool Mimicking Parasite Ova
The mushroom Agaricus blazei Murill from the Brazilian has been used as health food for the prevention of a range of diseases, including infection, allergy, and cancer. In this brief communication, I ...
A Giant Ovarian Tumour (7.5kg) During Pregnancy with its Successful Perinatal and Surgical Outcome
Here we are reporting an unusual case of a large ovarian tumour during pregnancy. A 26 years female with 8 months of amenorrhea presented with chief complaint of pain in abdomen and an ultrasonography...
Cell-Mediated and Humoral Immune Responses in the Sea-Star Asterias Rubens (Echinoderm): Notion of Invertebrate Primitive Antibody
The axial organ is considered as ancestral lymphoïd organ. It contains T-like and B-like sea star lymphocytes and Phagocytes. It plays a fundamental rôle in the sea star cell-mediated immune respons...
Immune Properties Corroborated By A. Rubens Sea Star Igkappa Gene
The sea star Igkappa gene was showing 2 Ig sites after its (star sea) immunization to Horse- radish peroxides (HRP), observed in 2013-14. The gene showed a specific immune response to the enzyme HRP a...
A Case Report of Psychosis in a Patient of Myxedema: Myxedema Madness
Myxedema is one of the most important causes of organic psychosis and sometimes can be missed. There are some cases showing extreme degree of hypothyroidism leading to psychiatric illnesses like mania...
Current Perspectives in the Management of Hypertension
Hypertension, more precisely, systemic arterial hypertension is one of the most prevalent non-communicable diseases worldwide. High blood pressure is the most common modifiable risk factor for cardiov...
Reactive Amyloidosis in a middle aged female with Behcet’s disease – Case report
Behcet’s disease is a multisystem vasculitis typically characterized by recurrent oral aphthae and genital ulcerations. Renal involvement in Behcet’s disease is less frequent and often less severe...
Medico-Legal Implications of Assessing and Treating the Aftermath of Trauma
A case involving a road traffic accident resulting in severe personal injuries was illustrated in the context of the medico-legal trail towards compensation. Key clinical and medico-legal issues were ...
Chlorinated Pyridazin-3-(2H)-ones as Novel Anti-Cancer Agents
Analogues of new lead structures, such as amido-2(5H)-furanones, bisarylated acrylic acids and 3(2H)-pyridazones, were prepared from mucochloric acid. Initially, these simple butenolides and analogues...
Severe Hypoglycemic Coma Event on MRI: Specific Brain Necrosis
With the widespread of sale and use of oral hypoglycemic drugs or insulin, hypoglycemic coma event have become a common medical emergency. Some patients with severe hypoglycemic coma led to prolonged ...
Nephropathy Associated With Prolong Lithium Administration
Lithium carbonate is often used for treatment of bipolar disorder, but caries various side effects affecting kidney function such as polyuria, impaired renal concentrating ability, impaired urinary ac...
Tubular Apocrine Adenoma - Case Report and Systematic Review
Tubular apocrine adenomas are relatively rare, benign, skin adnexal tumors with a limited number of cases reported in the literature. Herein is offered an additional case, as well as a thorough review...
Stent Fracture Following Recanalization of a Totally Occluded Artery: A Word of Caution
Although the dissection and re-entry strategy using the Crossboss and the Stingray system has increased procedural success, there is lack of evidence about the midterm efficacy of this approach. This ...
Cystic Neck Masses-A diagnostic and management challenge
Cervical metastasis is often the only presenting feature in patients with squamous cell carcinoma of the head and neck (HNSCC). These metastases frequently undergo cystic degeneration, and may be diff...
Association of Begomovirus with Okra (Abelmoschus esculentus L.) leaf curl virus disease in southern India
A severe leaf curl disease of Okra with high disease incidence and loss of production was observed during field survey of various locations of Southern India, and causal organism was identified as Beg...
Benchmarking the Hygiene of Utensils in Butcheries or Retail Stores
This study is benchmarking the hygiene of utensils (knives, cleavers, trays) for butchery stores within supermarkets. Aerobic Plate Count, Coliform count and E.coli count were used as indicators. Sa...
CT Gently: Personalizing CT and CBCT Imaging for the Children
Medical imaging procedures such as computed tomography (CT) and cone-beam computed tomography (CBCT) have been widely used in the diagnosis, detection and treatments of cancers worldwide. The achieved...
Chronotherapeutic Drug Delivery of Pectin Vs. Guar Gum, Xanthan Gum Controlled Release Colon Targeted Directly Compressed Propranolol Hcl Matrix Tablets
The study has been designed to develop a delayed release matrix tablets by using various natural polymers. The polsaccharide Pectin was used in the formulation Vs. Xanthan gum and Guar gum. The perfor...
A Rare Cause of Palpitations
An 87 years lady presented to the Acute Medical Unit with palpitations and breathlessness. She was haemodinamically stable and ECG was normal in sinus rhythm but cardiac monitoring demonstrated runs o...
Cancer informatics: a powerful approach to cancer research in the post-genomic age
Traditionally, the cancer biology has been an experimental science. However, with the advent of post-genomic age, the trend is shifting. The informatics approach is playing an increasingly important r...
Exploring the Transmissible Zoonotic Potential of Animal Prion Diseases
Mad Cow disease is a fatal and serious disease often found in Europe. Mad Cow disease, also known as Bovine Spongiform Encephalopathy, is often characterized by vacuoles found within the cytoplasm of ...
Comparative Analysis of Chemical, Fungal and Enzymatic Degradation of MCP
In general three different methods are used for the cleanup of pesticides. These include chemical, microbial and enzymatic methods. Therefore, the present study is an endeavor to compare the efficien...
Trigeminal Neuralgia - A Case Report with Review of Literature
Trigeminal neuralgia also known as ‘Fothergill’s disease’ or ‘tic douloureux’ is a very peculiar disease. The severe pain is paroxystic and can be triggered by a mild cutaneous stimulus on t...
Sub-Laminar Wiring in Spinal Fractures - A Viable Alternative
In Sri Lanka toddy tapping is a common form industry in the coast line villages. Falls from palm trees of forty feet is a common occupational hazard. Spinal fractures are common in these patients....
A Rapidly Progressive Hydatid Disease Imitating Metastatic Malignancy: An Unusual Multi-Organ Presentation. Report of a Case and Review of Literature
Hydatid disease is still a major health and socio-economic problem in endemic regions. It is the most frequent parasitic infection that commonly affects the liver and rarely involves multiple organs. ...
Suicidal Ligature Strangulation without a Knot - A Case Report
Strangulation is a form of death due to asphyxia. Suicide by ligature strangulation is rare & very unique. In suicidal strangulation, the signs of venous congestion are very well developed above the l...
Henoch-Scholein Purpura Nephritis in Children: A Severe IgA Mediated Glomerulonephritis
Henoch-SchÖlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) are common in children and characterized by IgA deposits in glomeruli. HSPN shows more severe glomerular lesions than IgAN; however...
Prevalence of Thyroid Abnormalities among Adults with HIV Infection in Oman
Thyroid dysfunction is a common endocrinopathy in HIV and occurs in 35% of all HIV infected adults. A retrospective cross-sectional design was used for the study. Adults with HIV infection attending t...
Sarcomatoid Carcinoma of Larynx: Case report
Sarcomatoid carcinoma is a rare form of laryngeal cancer which corresponds only 2-3% of all laryngeal cancers. This type of laryngeal cancer is presented mostly with hoarseness and dyspnea. On the end...
Court Obstetric – Pediatric Issues: Evidence-Based Practice
The article reviews the impact (or lack of it) of Evidence-Based Practice on obstetric - pediatric jurisprudence within the remit of the Bolam test. It briefly reviews the judicial outcome of the clas...
Human body via art
The human body is the entire structure of a human being and comprises a head, neck, trunk (which includes the thorax and abdomen), arms and hands, legs and feet. Every part of the body is composed of ...
Zirconia based Crowns for Esthetic Rehabilitation of Severely Discolored Teeth: A Case Report
According to studies, the smile is the first contact in human relationship. With the “media smile” in our society today, esthetic concerns of our patients are increasing. Despite the long-term rel...
Urinary Beta2-Microglobulin is a Sensitive Indicator for Renal Tubular Injury
After filtration through the glomeruli of the kidney, β2-microglobulin is reabsorbed by the renal proximal tubules. Increase in urinary β2-microglobulin indicates tubular dysfunction, and measuremen...
In vitro Antioxidant and Antimycobacterial Activity of Seeds of Piper longum Linn: A comparative Study
Piper longum, belonging to the family Piperaceae, have been reported to have pharmacological and clinical importance. The present study was undertaken to compare the in vitro antioxidant and antimycob...
Homicide-Suicide of an Older Couple Involving Complex Suicide: An Unusual Case
Homicide-suicide is defined by a homicide committed by someone who subsequently commits suicide. “Dyadic death” term has been also used for these deaths as these incidents often involve a pair of ...
Evaluation of Heart Block in Inferior Wall Myocardial Infarction in context of Intervention: Temporary Pacemaker Implantation Versus Conservative Medical Management, a Single Centre Experience from Eastern India
Association between Inferior wall Myocardial infarction (IWMI) and various degree of heart block is well known. However, most of these blocks are transient. Objective of this study was to re-evaluate ...
Public Mental Health Stigma and Mass Shootings
Mass shootings exert a strong influence on public policy and on public perception despite the fact that they are relatively rare. Mass shootings are defined by the Federal Bureau of Investigation (FB...
Recurrent Pleomorphic Adenoma of Submandibular Region
Salivary gland tumors are the 2-3% of all tumors and great majority of cases are pleomorphic adenomas. Pleomorphic adenomas are benign tumors but rarely seen as metastatic, recurrent or malign transf...
Esthetic Restoration of Two Severely Decayed Maxillary Central Incisors: A Case Report
Materials selection is the second in the series on crowns and other extra-coronal restorations. Some of us are less than inspired by dental materials science. Restoration of an anterior root-filled to...
Study of Zinc Oxide Nanofluids for Heat Transfer Application
This paper describes preparation of zinc oxide (ZnO) based nanofluids in polymer matrix. The rheological properties of nanofluid were studied and were applied in heat transfer application....
Parkinson’s Disease in the Very Old – Clinicopathological Observations
The incidence of Parkinson syndrome (PS) increases dramatically after age 80 years. As the number of the very old (>80 years) is rising in the population, the number of PS cases would increase....
Dry Socket Following Teeth Extraction: Effect of Excessive Socket Saline Irrigation
Alveolar osteitis, “dry socket”, is reported among the most common complications following teeth extraction. Many controversies are present in the literature of the pathogenesis of alveolar osteit...
Crouzon Syndrome - A Case Report of Rare Genetic Disorder with Review of Literature
In 1912, a French neurologist, Octave Crouzon (1874-1938) first described the crouzon syndrome and in 1937 Atkinson reviewed eighty six cases that were published and found about 67% of the cases were ...
Self-Report Justifications for Serial Sex Murder: An Exploratory Study of Neutralization Techniques
Thirty-eight out of seventy-five convicted serial sex murderers returned a survey which asked them to indicate their reasons for committing the crime of first degree murder along with at least one sex...
Evaluation of Pharmacologically Interesting Dose Range of Ascorbic Acid in Mice
Ascorbic acid is the most abundant water-soluble naturally occurring organic compound with antioxidant properties. It serves as a cofactor for enzymes involved in hormone biosynthesis, and the regener...
History of Nazi Dental Gold: From Dead Bodies till Swiss Bank
The SS Reichsfürher Heinrich Himmler, on the 23rd of September 1940 gave the SS doctors orders to collect the golden teeth in the mouth of the dead. Everybody knows that....
Bacterial Biofilm: Dispersal and Inhibition Strategies
Bacterial biofilms are communities of microorganisms residing within a polysaccharide matrix. Dental plaque, slimy coating in tanks, and algal mats on bodies of water are examples of biofilms. It is w...
On Chronophysiomics: Prospects to Optimize Appetite and Health
This editorial describes evolving chronophysiomical mediations of appetite and food intake (AFI). Chronophysiomics is a multiscience involving integrated chronophysiology and functional omics biotechn...
Metformin like Stress Response Modulating Effects of Turmeric Curcuminoids in Mice
The aim of the study was to compare the protective efficacies of a single and repeated daily oral doses (5, 20, 80, and 320 mg/kg) of a Curcuma longa extract (C. longa) enriched in curcuminoids (95.4%...
Parietal Bone Metastasis of Rectal Adenocarcinoma as an Initial Diagnosis of Recurrence: Case Report
The most common metastatic sites of colorectal cancer are the regional lymph nodes, liver, lung, and peritoneum. Parietal bone metastasis without vertebral bone metastasis from colorectal cancer is an...