Dr. Mohammed Nayeem is an Assistant Professor in the Department of Physiology & Pharmacology, Center for Cardiovascular & Respiratory Sciences, School of Medicine, West Virginia University, USA. He is also an Adjunct Assistant Professor in the Department of Pharmaceuticals and Pharmacological Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, USA. He obtained his B.Sc., M.Sc. and PhD in Life Science/Biochemistry/Immunology from Osmania University, Hyderabad, India. He worked in Medical College of Virginia, Virginia Commonwealth University, VA, USA, Brody School of Medicine, East Carolina University, NC, USA and NIEHS/NIH, NC, USA.
Dr. Mohammed Nayeem funded T32 AG052375-01A1 (NIA/NIH); 1,749,540.00, start date 06/01/2017 and end date 05/31/2022, He as a Collaborator in the Project entitled, “Predoctoral Training in Stroke and its Co-Morbidities” (FUNDED & ACTIVE). Also he got his other R25 grant (NHLBI/NIH; $580,859.00), starting from 1-1-2017 and 12-31-2021, He as a Collaborator in the Project entitled “The Hampton University Summer Pharmacy Experiences in Academic Research (SPEAR) Program” (FUNDED & ACTIVE). He got his R01 funded as a Principal Investigator with excellent score from NHLBI/NIH (2013) on Role of Cyp2j-epoxygenases, sEH and PPARs in adenosine-induced vascular response. Also he got his other R01 funded as a CO-Investigator with also excellent score from NHLBI/NIH (2008) on Role of CYP P450s in the Regulation of Vascular Tone through Adenosine Receptors
Dr. Mohammed Nayeem got many other awards and honors. He has published many research papers in reputed and peer-reviewed journals related to cardiovascular pharmacology, cardiovascular physiology and in Molecular Cellular Biochemistry, Naunyn Schmiedebergs Archives Pharmacology, Journal Molecular Cellular Cardiology, Antioxidant Redox Signaling, etc. He is member of various societies including American Heart Association, American Physiology Society, International Society of Heart Research (American Section), American Society for Pharmacology and Experimental Therapeutics, Microcirculatory Society. His research interest covers many aspects of Cardiovascular Pharmacology including Role of adenosine receptors in the regulation of vascular tone through cyp-epoxygenases, soluble epoxide hydrolase and omega hydroxylase; the regulation of vascular tone through the generation of EETs, DHETs and 20-HETE; the regulation of vascular tone through the adenylyl cyclase cAMP and PKA signaling; the regulation of vascular tone through peroxisome proliferator-activated receptors (PPARs); the regulation of vascular tone through ATP-sensitive (KATP) channels.
Dr. Mohammed Nayeem is interested in understanding the role of epoxygenases, soluble epoxide hydrolase, ω-hydroxylases, arachidonic acids-derived oxylipins and PPARγ in transgenic mouse models for hypertension, salt-sensitive hypertension and coronary hyperemic response, and their therapeutic targets.
